What Is Des(1-3)IGF-1?
IGF-1 LR3 Pack 1mg
The "Des" prefix is standard peptide-chemistry shorthand for "deleted," and "(1-3)" identifies which residues were removed — in this case, the first three of the 70 amino acids that make up native human IGF-1. This is a smaller, more conservative structural change than the modification used to build IGF-1 LR3, which instead adds 13 residues.
Published in-vitro research on Des(1-3)IGF-1 has generally found it retains strong IGF-1 receptor binding while showing reduced affinity for circulating IGF-binding proteins compared to native IGF-1 — the same general research rationale that applies to IGF-1 LR3, achieved through a different structural route. Both variants appear in the growth-factor research literature as tools for studying prolonged IGF-1 receptor activity.
Des(1-3)IGF-1 is an unregulated research chemical, not an approved human or veterinary therapeutic anywhere. IGF-1 LR3 is listed on revivelab.ae as the IGF-1 LR3 pack (1 mg); this page describes the compound and gives no guidance on its use.
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